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06/30 More Progress in Understanding Neuroendocrine Tumors from Johns Hopkins University

Scientists from Johns Hopkins University have uncovered more information about the genetics of pancreatic neuroendocrine tumors!

05/23 SUTENT Granted Approval for Treatment of Patients with Pancreatic Neuroendocrine Tumors

The US Food and Drug Administration (FDA) has granted approval to Pfizer, Inc. for SUTENT ® (sunitinib malate) to treat patients with pancreatic neuroendocrine tumors.

02/14 The New England Journal of Medicine Reports Progress in Treating Pancreatic Neuroendocrine Tumors

Three articles published last week in the New England Journal of Medicine highlight recent progress in treating pancreatic neuroendocrine tumors:

01/21 Funded Researchers Illuminate Genetic Code for a Form of Pancreatic Cancer

BOSTON, Jan. 20, 2011 /PRNewswire-USNewswire/ -- Through a grant provided by the Caring for Carcinoid Foundation (www.caringforcarcinoid.org), researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center have discovered several key mutations in pancreatic neuroendocrine tumors. This significant finding holds the promise of improving patient diagnosis and treatment and brings the neuroendocrine cancer community closer to a cure. Neuroendocrine cancers affect approximately 100,000 patients in the United States, including, according to published reports, Steve Jobs, CEO of Apple Inc.

01/20 CFCF-FUNDED RESEARCHERS ILLUMINATE GENETIC CODE FOR PANCREATIC NEUROENDOCRINE TUMORS!

With great excitement, we announce the publication of significant and highly promising research results in Science, one of the world’s most prestigious scientific journals.

12/22 International Collaboration Essential for Rare Cancer Clinical Trials

On December 10, the National Cancer Institute (NCI) and the American Society of Clinical Oncology convened a meeting to explore ways to collaborate across borders on clinical trials for rare cancers. The meeting brought together nearly 100 representatives from 75 institutions, including the National Institute of Health's Office for Rare Disease Research, the US Department of Health and Human Services, and the Food and Drug Administration.

12/10 First Targeted Therapy Approved for the Treatment of Pancreatic Neuroendocrine Tumors in Europe

On December 2nd, Pfizer Inc. announced that the European Commission has approved Sutent for the treatment of unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumors with disease progression in adults.

11/23 Researchers Uncover New Characteristics of Pancreatic Cancer Growth and Suggest Approaches to Prevention

The pace of pancreatic cancer growth may be slower than the medical community has assumed. A recent collaborative study by cancer researchers at the Johns Hopkins University and Sanger Institute  examined tissue from pancreatic cancer patients and found that cells in the pancreas took at least ten years to mutate enough to produce cancer cells and seven more years to develop enough to become capable of spreading to other organs.

According to the National Cancer Institute, in 2010 there will be more than 36,000 deaths from pancreatic cancer and more than 43,000 new cases in the United States. Compared with other cancers, the length of survival after pancreatic cancer diagnosis is unfavorable, with only 6% of patients surviving for five years or more after diagnosis.

11/05 Phase III Trial Confirms Sunitinib Improves Progression-Free Survival Among Pancreatic Neuroendocrine Tumor Patients

A retrospective, independent central review confirmed the benefit of sunitinib (Sutent) in extending progression-free survival among pancreatic neuroendocrine tumor patients. This analysis the original of phase-III trial showed that the median progression-free survival was 11.1 months with sunitinib versus 5.5 months with placebo.

11/05 RADIANT Trials Find Everolimus to Improve Progression-Free Survival for Advanced Pancreatic Neuroendocrine Tumors and Carcinoid Tumors

Findings from international RADIANT Phase III trials on everolimus (Afinitor) were presented at the 35th European Society for Medical Oncology Congress in Milan, Italy last month.

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