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Dave, Suzi, and Lauren at 2011 Focus on Neuroendocrine Tumors Conference in Philadelphia, PA

Dave, Suzi, Lauren - Philadelphia, PA

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Exciting New Research

Wednesday, January 22, 2014

I am very pleased to begin 2014 by highlighting one of the Caring for Carcinoid Foundation’s breakthrough achievements of 2013.  Dr. Matthew Meyerson, Director of the Center for Cancer Genome Discovery at the Dana Farber Cancer Institute, published the results of a next-generation sequencing study of neuroendocrine tumors of the small intestine in Nature Genetics.

CFCF Awards New Research Grant to Dr. Eric Nakakura

Wednesday, December 12, 2012

The Caring for Carcinoid Foundation is pleased to announce the latest grant award through our grant-making partnership with the American Association for Cancer Research to Eric Nakakura from the University of California, San Francisco to overcome resistance to mTOR inhibition in pancreatic neuroendocrine tumor patients. 

The mammalian target of rapamycin (mTOR) is a protein involved in many cellular pathways including cell growth and death.  In neuroendocrine tumors, mTOR can become disregulated and consequently promote tumor cell growth. CFCF-funded scientists at Johns Hopkins University identified mutations in the mTOR signaling pathway among patients with non-functioning pancreatic neuroendocrine tumors (Jiao, 2011).

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